Drug Information

Drug General Information
Drug ID
D06VXY
Former ID
DIB015899
Drug Name
SB-237376
Drug Type
Small molecular drug
Indication Arrhythmia [ICD9: 427; ICD10:I47-I49] Terminated [526551]
Company
SmithKline Beecham plc
Formula
C20H25N3O5
Canonical SMILES
COc1ccc(CCNCCCNC(=O)c2ccc(cc2)[N+](=O)[O-])cc1OC
InChI
1S/C20H25N3O5/c1-27-18-9-4-15(14-19(18)28-2)10-13-21-11-3-12-22-20(24)16-5-7-17(8-6-16)23(25)26/h4-9,14,21H,3,10-13H2,1-2H3,(H,22,24)
InChIKey
XEAKAKKNLOUHDV-UHFFFAOYSA-N
PubChem Compound ID
9845214
Target and Pathway
Target(s) Calcium channel Target Info Modulator [526551]
Potassium channel Target Info Modulator [526551]
References
Ref 526551Electrophysiologic effects of SB-237376: a new antiarrhythmic compound with dual potassium and calcium channel blocking action. J Cardiovasc Pharmacol. 2003 Mar;41(3):414-21.
Ref 526551Electrophysiologic effects of SB-237376: a new antiarrhythmic compound with dual potassium and calcium channel blocking action. J Cardiovasc Pharmacol. 2003 Mar;41(3):414-21.

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