Drug Information

Drug General Information
Drug ID
D05IVZ
Former ID
DIB010028
Drug Name
RU-33965
Drug Type
Small molecular drug
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Terminated [544965]
Company
Aventis Pharma AG
Formula
C16H15N3O2
Canonical SMILES
c12n(cnc1C(=O)C1CC1)c1c(C(=O)N(C2)C)cccc1
CAS Number
CAS 122321-05-5
PubChem Compound ID
129696
Target and Pathway
Target(s) GABA A receptor Target Info Modulator [526780]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 544965Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001729)
Ref 526780Discriminative stimulus properties of RU 33965, a benzodiazepine receptor weak partial inverse agonist. Pharmacol Biochem Behav. 1992 Oct;43(2):583-8.

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