Drug Information

Drug General Information
Drug ID
D04ZWQ
Former ID
DIB007011
Drug Name
Org-25435
Drug Type
Small molecular drug
Indication Epilepsy [ICD10:G40] Phase 1 [522942]
Company
Organon BioSciences
Formula
C19H31NO6
Canonical SMILES
c1(OC(=O)[C@H](N(CCOC)CCOC)CC)c(cc(cc1OC)C)OC
PubChem Compound ID
11036024
Target and Pathway
Target(s) GABA A receptor Target Info Modulator [530997]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 522942ClinicalTrials.gov (NCT01062867) First Administration to Man Of Org 25435 a New Intravenous Anesthetic. U.S. National Institutes of Health.
Ref 530997First administration to man of Org 25435, an intravenous anaesthetic: A Phase 1 Clinical Trial. BMC Anesthesiol. 2010 Jun 29;10:10.

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