Drug Information

Drug General Information
Drug ID
D09ZVR
Former ID
DIB004780
Drug Name
MDL-43291
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Terminated [544539]
Company
Hoechst Marion Roussel Inc
Formula
C25H42O4S
Canonical SMILES
[C@@H]12[C@H](SCC(=O)O)/C(=C\CCCCCCCCCCCCC)/CC[C@@H]2CC<br />C(=O)O1
CAS Number
CAS 129357-91-1
PubChem Compound ID
3036016
Target and Pathway
Target(s) Cysteinyl leukotriene receptor 1 Target Info Modulator
Leukotriene CysLT2 receptor Target Info Modulator
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interactionhsa04020:Calcium signaling pathway
Neuroactive ligand-receptor interaction
NetPath Pathway TGF_beta_Receptor Signaling Pathway
IL4 Signaling Pathway
IL3 Signaling PathwayNetPath_16:IL4 Signaling Pathway
IL3 Signaling Pathway
Pathway Interaction Database Endothelinsendothelinpathway:Endothelins
Reactome Leukotriene receptors
G alpha (q) signalling eventsR-HSA-391906:Leukotriene receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
GPCR downstream signaling
References
Ref 544539Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000087)

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