Drug Information

Drug General Information
Drug ID
D0T5MB
Former ID
DIB015358
Drug Name
Lu-35138
Indication Psychotic disorders [ICD9: 290-299; ICD10:F20-F29] Discontinued in Phase 2 [547224]
Company
H Lundbeck A/S
Canonical SMILES
C1N(c2c([C@@H]1CCC1CC(=CCN1)c1c[nH]c3c1ccc(c3)Cl)cccc2)<br />C(=O)C
Target and Pathway
Target(s) D(4) dopamine receptor Target Info Antagonist [547225]
KEGG Pathway Neuroactive ligand-receptor interaction
Dopaminergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Dopamine receptor mediated signaling pathway
Nicotine pharmacodynamics pathway
Reactome Dopamine receptors
G alpha (i) signalling events
WikiPathways Hypothetical Network for Drug Addiction
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Genes and (Common) Pathways Underlying Drug Addiction
GPCR ligand binding
GPCR downstream signaling
Nicotine Activity on Dopaminergic Neurons
GPCRs, Other
References
Ref 547224Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014237)
Ref 547225Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014237)

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.