Drug Information

Drug General Information
Drug ID
D0AZ5V
Former ID
DIB006723
Drug Name
L-698544
Synonyms
CNDQ
Drug Type
Small molecular drug
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Terminated [545425]
Company
Merck & Co Inc
Formula
C9H7ClN2O3
Canonical SMILES
C1([N+](=O)[O-])C(=O)Nc2c(C1)ccc(c2)Cl
CAS Number
CAS 147778-05-0
PubChem Compound ID
10220180
Target and Pathway
Target(s) Glutamate receptor AMPA subtype Target Info Antagonist [533941]
NMDA receptor Target Info Modulator [533941]
References
Ref 545425Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003218)
Ref 5339413-Nitro-3,4-dihydro-2(1H)-quinolones. Excitatory amino acid antagonists acting at glycine-site NMDA and (RS)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. J Med Chem. 1993 Oct 29;36(22):3397-408.

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