TTD | Drug: D04DMO

Drug General Information
Drug ID	D04DMO
Former ID	DIB005811
Drug Name	FR-194738
Drug Type	Small molecular drug
Indication	Hypercholesterolemia [ICD10:E78]		Terminated	[546677]
Company	Fujisawa Pharmaceutical Co Ltd
Formula	C27H38ClNO2S
Canonical SMILES	C(#CC(C)(C)C)/C=C/CN(Cc1cc(OCC(OCc2cscc2)(C)C)ccc1)CC.C<br />l
CAS Number	CAS 204067-52-7
PubChem Compound ID	9869566
Target and Pathway
Target(s)	Squalene monooxygenase	Target Info	Modulator	[526940]
KEGG Pathway	Steroid biosynthesis
	Sesquiterpenoid and triterpenoid biosynthesis
	Metabolic pathways
	Biosynthesis of secondary metabolites
	Biosynthesis of antibiotics
PathWhiz Pathway	Steroid Biosynthesis
Reactome	Cholesterol biosynthesis
Reactome	Activation of gene expression by SREBF (SREBP)
References
Ref 546677	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009590)
Ref 526940	Synthesis and biological activity of a novel squalene epoxidase inhibitor, FR194738. Bioorg Med Chem Lett. 2004 Feb 9;14(3):633-7.

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Drug Information