Drug Information

Drug General Information
Drug ID
D0T6MU
Former ID
DIB012313
Drug Name
FR-113680
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Terminated [544862]
Company
Fujisawa Pharmaceutical Co Ltd
Formula
C35H39N5O6
Canonical SMILES
n1(cc(c2c1cccc2)C[C@H](C(=O)N[C@H](C(=O)N(Cc1ccccc1)C)C<br />c1ccccc1)NC(=O)[C@@H](NC(=O)C)[C@H](O)C)C=O
CAS Number
CAS 126088-92-4
PubChem Compound ID
130848
Target and Pathway
Target(s) Substance-P receptor Target Info Inhibitor [526802]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Measles
PANTHER Pathway CCKR signaling map ST
Reactome G alpha (q) signalling events
WikiPathways SIDS Susceptibility Pathways
Gastrin-CREB signalling pathway via PKC and MAPK
Spinal Cord Injury
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 544862Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001352)
Ref 526802FR 113680: a novel tripeptide substance P antagonist with NK1 receptor selectivity. Br J Pharmacol. 1992 May;106(1):123-6.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.