Drug Information

Drug General Information
Drug ID
D0YP0C
Former ID
DIB009081
Drug Name
DT-TX-30
Synonyms
DT-TX-30-SE
Indication Angina pectoris [ICD9: 413; ICD10:I20] Phase 1 [534431]
Company
Boehringer Ingelheim Corp
Canonical SMILES
S(=O)(=O)(c1ccc(cc1)Cl)NCCc1ccc(/C(=C\CCCC(=O)O)/c2cncc<br />c2)cc1
CAS Number
CAS 127369-68-0
Target and Pathway
Target(s) Thromboxane A2 receptor Target Info Antagonist [534431]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Platelet activation
Reactome Prostanoid ligand receptors
G alpha (q) signalling events
G alpha (12/13) signalling events
Thromboxane signalling through TP receptor
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Small Ligand GPCRs
Signal amplification
GPCR ligand binding
GPCR downstream signaling
References
Ref 534431DTTX30, a combined thromboxane receptor antagonist and thromboxane synthetase inhibitor, prevents coronary thrombosis in anesthetized dogs. Basic Res Cardiol. 1997 Jun;92(3):181-90.
Ref 534431DTTX30, a combined thromboxane receptor antagonist and thromboxane synthetase inhibitor, prevents coronary thrombosis in anesthetized dogs. Basic Res Cardiol. 1997 Jun;92(3):181-90.

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