Drug Information

Drug General Information
Drug ID
D00FYF
Former ID
DNC005423
Drug Name
NVP-DPP728
Drug Type
Small molecular drug
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Discontinued in Phase 2 [547061]
Formula
C15H18N6O
Canonical SMILES
C1CC(N(C1)C(=O)CNCCNC2=NC=C(C=C2)C#N)C#N
InChI
1S/C15H18N6O/c16-8-12-3-4-14(20-10-12)19-6-5-18-11-15(22)21-7-1-2-13(21)9-17/h3-4,10,13,18H,1-2,5-7,11H2,(H,19,20)/t13-/m0/s1
InChIKey
VFFZWMWTUSXDCB-ZDUSSCGKSA-N
PubChem Compound ID
9796290
Target and Pathway
Target(s) Dipeptidyl peptidase IV Target Info Inhibitor [529262]
KEGG Pathway Protein digestion and absorption
NetPath Pathway IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
References
Ref 547061Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012640)
Ref 529262Eur J Med Chem. 2008 Aug;43(8):1603-11. Epub 2007 Nov 29.A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors.

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