Drug Information

Drug General Information
Drug ID
D0E7BP
Former ID
DIB000118
Drug Name
CP-663427
Synonyms
LNK-427; OSI-427
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Terminated [547153]
Company
Pfizer Inc
Canonical SMILES
n1(c(=O)cc(c2c1ccc(C(c1n(cnc1)C)(c1cnc(cc1)Cl)N)c2)c1cc<br />(Cl)ccc1)CC1CC1
CAS Number
CAS 288391-21-9
Target and Pathway
Target(s) Protein farnesyltransferase beta subunit Target Info Inhibitor [550155]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
References
Ref 547153Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013446)
Ref 550155WO patent application no. 2011,0881,26, Treatment of viral infection with prenyltransferase inhibitors.

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