TTD | Drug: D01SBP

Drug General Information
Drug ID	D01SBP
Former ID	DIB014553
Drug Name	Co-152791
Indication	Epilepsy [ICD10:G40]		Terminated	[546908]
Company	Purdue Neuroscience Corp
Canonical SMILES	[C@@]12([C@H]([C@H]3[C@@H]([C@@]4([C@H](C[C@@](C#Cc5ccc<br />(C(=O)C)cc5)(CC4)O)CC3)C)CC2)CC[C@@H]1C(=O)C)C
CAS Number	CAS 162882-63-5
Target and Pathway
Target(s)	GABA A receptor	Target Info	Modulator	[534715]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
Reactome	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 546908	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011029)
Ref 534715	Substituted 3beta-phenylethynyl derivatives of 3alpha-hydroxy-5alpha-pregnan-20-one: remarkably potent neuroactive steroid modulators of gamma-aminobutyric acidA receptors. J Pharmacol Exp Ther. 1998Oct;287(1):198-207.

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Drug Information