Drug Information

Drug General Information
Drug ID
D08WCU
Former ID
DIB005253
Drug Name
BMS-180448
Drug Type
Small molecular drug
Indication Angina pectoris [ICD9: 413; ICD10:I20] Discontinued in Phase 2 [545720]
Company
Bristol-Myers Squibb Co
Formula
C20H18ClN5O2
Canonical SMILES
[C@H]1(c2c(OC([C@H]1O)(C)C)ccc(C#N)c2)N/C(=N/C#N)/Nc1cc<br />c(Cl)cc1
CAS Number
CAS 144301-94-0
PubChem Compound ID
122031
Target and Pathway
Target(s) Potassium channel Target Info Agonist [534264]
References
Ref 545720Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004365)
Ref 534264The novel cardioprotective agent BMS-180448 activates a potassium conductance in cardiac and vascular smooth muscle. Naunyn Schmiedebergs Arch Pharmacol. 1996 Oct;354(4):444-51.

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