Drug Information

Drug General Information
Drug ID
D07EGW
Former ID
DIB011478
Drug Name
AE-0047
Synonyms
Calbren; Vatanidipine; Watanidipine hydrochloride; GJ-0956; (R)-(-)-AE 0047; (S)-(+)-AE 0047
Drug Type
Small molecular drug
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Discontinued in Preregistration [545033]
Company
Mitsubishi Pharma Corp
Formula
C41H44Cl2N4O6
Canonical SMILES
C1(=C(NC(=C(C1c1cc([N+](=O)[O-])ccc1)C(=O)OCCc1ccc(N2CC<br />N(C(c3ccccc3)c3ccccc3)CC2)cc1)C)C)C(=O)OC.Cl.Cl
PubChem Compound ID
154437
Target and Pathway
Target(s) Calcium channel Target Info Modulator [534512]
References
Ref 545033Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001931)
Ref 534512AE0047-mediated calcium channel blocking in vascular smooth muscles. Gen Pharmacol. 1997 Sep;29(3):337-43.

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