Drug Information

Drug General Information
Drug ID
D07VIK
Former ID
DAP001333
Drug Name
Arsenic trioxide
Synonyms
Arsenox; Arsentrioxide; Naonobin; Trisenox; Trixenox; Acide arsenieux [French]; Anhydride arsenieux [French]; Arseni trioxydum; Arsenic blanc [French]; Arsenic trioxide [JAN]; Arsenigen saure [German]; Arsenious Acid Anhydride; Arsenious trioxide; Arsenous oxide [ISO]; Oxyde Arsenieux; Arsenic trioxide [UN1561] [Poison]; Arsenic oxide (As2O3); Arsenic(III) trioxide; Oxyde Arsenieux [ISO-French]; Trisenox (TN); Arsenic trioxide (JP15/USAN); Arsenic(3+); Oxygen(2-)
Drug Type
Small molecular drug
Indication Acute lymphoblastic leukemia [ICD9: 204.0, 556; ICD10:C91.0] Approved [538332], [551871]
Therapeutic Class
Anticancer Agents
Formula
As2O3
Canonical SMILES
[O-2].[O-2].[O-2].[As+3].[As+3]
InChI
1S/2As.3O/q2*+3;3*-2
InChIKey
QTLQKAJBUDWPIB-UHFFFAOYSA-N
CAS Number
CAS 1327-53-3
PubChem Compound ID
14888
PubChem Substance ID
853981, 29282900, 49854936, 57328779, 77866200, 104335670, 126409444, 126691141, 134981320, 164806579, 180680593, 184609025, 252559753
ChEBI ID
ChEBI:30621
SuperDrug ATC ID
L01XX27
SuperDrug CAS ID
cas=001327533
Drug Resistance Mutation (DRM)
DRM DRM Info
Target and Pathway
Target(s) Malignant cancer cells Target Info Inhibitor [535399], [535551]
References
Ref 538332FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 078729.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 535399Arsenic trioxide in multiple myeloma: rationale and future directions. Cancer J. 2002 Jan-Feb;8(1):12-25.
Ref 535551How acute promyelocytic leukaemia revived arsenic. Nat Rev Cancer. 2002 Sep;2(9):705-13.

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