Drug Information

Drug General Information
Drug ID
D00DIF
Former ID
DIB019680
Drug Name
CyPPA
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539470]
Formula
C16H23N5
InChI
InChI=1S/C16H23N5/c1-11-10-15(18-14-7-5-4-6-8-14)19-16(17-11)21-13(3)9-12(2)20-21/h9-10,14H,4-8H2,1-3H3,(H,17,18,19)
InChIKey
USEMRPYUFJNFQN-UHFFFAOYSA-N
PubChem Compound ID
909822
PubChem Substance ID
1159006, 4771447, 9195752, 25665763, 44509793, 46497387, 49699829, 50526756, 88258261, 90340684, 103647907, 104118715, 110085298, 121298541, 121361699, 135650151, 135698352, 162248103, 163133782, 163375797, 163563919, 163564661, 163838085, 166716506, 170558751, 175612513, 223532337, 229268723, 248514668, 249827909, 250201140, 252059710, 252156899, 252229796, 252425571, 252552971
Target and Pathway
Target(s) KCa2.2 Target Info Activator [528824]
KCa2.3 Target Info Activator [528824]
References
Ref 539470(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2323).
Ref 528824Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca2+-activated K+ channels. Br J Pharmacol. 2007 Jul;151(5):655-65. Epub 2007 May 8.

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