TTD | Drug: D04UYO

Drug General Information
Drug ID	D04UYO
Former ID	DNC011959
Drug Name	HMR-1556
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539668]
Formula	C18H26F3NO5S
InChI	InChI=1S/C18H26F3NO5S/c1-5-28(24,25)22(4)15-13-11-12(26-10-6-9-18(19,20)21)7-8-14(13)27-17(2,3)16(15)23/h7-8,11,15-16,23H,5-6,9-10H2,1-4H3/t15-,16+/m0/s1
InChIKey	YBZQPPIQXNWGEX-JKSUJKDBSA-N
PubChem Compound ID	9867091
PubChem Substance ID	14831924, 14880565, 24158751, 45289357, 77289224, 135650352, 136057873
Target and Pathway
Target(s)	Potassium voltage-gated channel subfamily KQT member 1	Target Info	Inhibitor	[526979]
KEGG Pathway	Adrenergic signaling in cardiomyocytes
	Cholinergic synapse
	Gastric acid secretion
	Pancreatic secretion
	Protein digestion and absorption
	Vibrio cholerae infection
PathWhiz Pathway	Muscle/Heart Contraction
Reactome	Voltage gated Potassium channels
WikiPathways	SIDS Susceptibility Pathways
	Potassium Channels
	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
	TarBasePathway
References
Ref 539668	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2590).
Ref 526979	J Med Chem. 2004 Mar 11;47(6):1303-14.Selective optimization of side activities: another way for drug discovery.

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Drug Information