Drug Information

Drug General Information
Drug ID
D05IVD
Former ID
DNC012111
Drug Name
PREUSSOMERIN
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534466]
Formula
C20H10O7
Canonical SMILES
C1=CC2=C3C(=C1)OC45C6C(O6)C(=O)C7=C(C=CC(=C74)OC3(O5)C=<br />CC2=O)O
InChI
1S/C20H10O7/c21-9-6-7-19-14-8(9)2-1-3-11(14)26-20(27-19)15-12(25-19)5-4-10(22)13(15)16(23)17-18(20)24-17/h1-7,17-18,22H/t17?,18?,19-,20+/m1/s1
InChIKey
YMTRIUFFDHMDKK-TUNPWDSISA-N
PubChem Compound ID
44332169
Target and Pathway
Target(s) Protein farnesyltransferase beta subunit Target Info Inhibitor [534466]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
References
Ref 534466J Med Chem. 1997 Sep 12;40(19):2971-90.Ras farnesyltransferase: a new therapeutic target.
Ref 534466J Med Chem. 1997 Sep 12;40(19):2971-90.Ras farnesyltransferase: a new therapeutic target.

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