Drug Information

Drug General Information
Drug ID
D0J2UA
Former ID
DNC009448
Drug Name
6-bromoaplysinopsin
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526321]
Formula
C14H13BrN4O
Canonical SMILES
CN1C(=CC2=CNC3=C2C=CC(=C3)Br)C(=O)N(C1=N)C
InChI
1S/C14H13BrN4O/c1-18-12(13(20)19(2)14(18)16)5-8-7-17-11-6-9(15)3-4-10(8)11/h3-7,16-17H,1-2H3/b12-5+,16-14?
InChIKey
OVVZEMAUZWSOHR-ZSUDRMHPSA-N
PubChem Compound ID
10404564
Target and Pathway
Target(s) 5-hydroxytryptamine 2A receptor Target Info Inhibitor [526321]
5-hydroxytryptamine 2C receptor Target Info Inhibitor [526321]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channelshsa04020:Calcium signaling pathway
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathwayP04374:5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling eventsR-HSA-390666:Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and STAT3 Signaling
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP732:Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
References
Ref 526321J Nat Prod. 2002 Apr;65(4):476-80.New antiinfective and human 5-HT2 receptor binding natural and semisynthetic compounds from the Jamaican sponge Smenospongia aurea.
Ref 526321J Nat Prod. 2002 Apr;65(4):476-80.New antiinfective and human 5-HT2 receptor binding natural and semisynthetic compounds from the Jamaican sponge Smenospongia aurea.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.