Drug Information

Drug General Information
Drug ID
D06TVS
Former ID
DNC013251
Drug Name
N1-benzyl-N3-hydroxy-2-isobutylmalonamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528501]
Formula
C14H20N2O3
Canonical SMILES
CC(C)CC(C(=O)NCC1=CC=CC=C1)C(=O)NO
InChI
1S/C14H20N2O3/c1-10(2)8-12(14(18)16-19)13(17)15-9-11-6-4-3-5-7-11/h3-7,10,12,19H,8-9H2,1-2H3,(H,15,17)(H,16,18)
InChIKey
BOQZRPQZGWWCDJ-UHFFFAOYSA-N
PubChem Compound ID
16116576
Target and Pathway
Target(s) Aminopeptidase N Target Info Inhibitor [528501]
BioCyc Pathway Glutathione-mediated detoxification
KEGG Pathway Glutathione metabolism
Metabolic pathways
Renin-angiotensin system
Hematopoietic cell lineage
Pathway Interaction Database C-MYB transcription factor network
PathWhiz Pathway Glutathione Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways Metabolism of Angiotensinogen to Angiotensins
Cardiac Progenitor Differentiation
miR-targeted genes in squamous cell - TarBase
miR-targeted genes in muscle cell - TarBase
miR-targeted genes in lymphocytes - TarBase
miR-targeted genes in leukocytes - TarBase
Glutathione metabolism
References
Ref 528501Bioorg Med Chem. 2007 Jan 1;15(1):63-76. Epub 2006 Oct 12.A library of novel hydroxamic acids targeting the metallo-protease family: design, parallel synthesis and screening.
Ref 528501Bioorg Med Chem. 2007 Jan 1;15(1):63-76. Epub 2006 Oct 12.A library of novel hydroxamic acids targeting the metallo-protease family: design, parallel synthesis and screening.

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