Drug Information

Drug General Information
Drug ID
D00OCV
Former ID
DNC005855
Drug Name
3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-ol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527668]
Formula
C13H18N2O
Canonical SMILES
CC1=C(C2=C(N1)C=CC=C2O)CCN(C)C
InChI
1S/C13H18N2O/c1-9-10(7-8-15(2)3)13-11(14-9)5-4-6-12(13)16/h4-6,14,16H,7-8H2,1-3H3
InChIKey
HXNGZUVNHQYMKL-UHFFFAOYSA-N
PubChem Compound ID
44404892
Target and Pathway
Target(s) 5-hydroxytryptamine 2A receptor Target Info Inhibitor [527668]
5-hydroxytryptamine 2C receptor Target Info Inhibitor [527668]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channelshsa04020:Calcium signaling pathway
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathwayP04374:5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling eventsR-HSA-390666:Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and STAT3 Signaling
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP732:Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
References
Ref 527668Bioorg Med Chem Lett. 2005 Oct 15;15(20):4555-9.SAR of psilocybin analogs: discovery of a selective 5-HT 2C agonist.
Ref 527668Bioorg Med Chem Lett. 2005 Oct 15;15(20):4555-9.SAR of psilocybin analogs: discovery of a selective 5-HT 2C agonist.

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