Drug Information

Drug General Information
Drug ID
D0FZ6A
Former ID
DIB019772
Drug Name
dodecylphosphate
Synonyms
FAP12; dodecanol phosphate; FAP-12; lauryl phosphate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540635]
Formula
C12H25O4P-2
InChI
InChI=1S/C12H27O4P/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15/h2-12H2,1H3,(H2,13,14,15)/p-2
InChIKey
TVACALAUIQMRDF-UHFFFAOYSA-L
PubChem Compound ID
1550836
PubChem Substance ID
32250188, 57409123, 79756315, 110473820, 137129059, 143475252, 163305549, 178100857, 201504671, 204366699, 224813771
Target and Pathway
Target(s) LPA2 receptor Target Info Agonist [526598]
Lysophosphatidate-3 receptor Target Info Antagonist [526598]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
PI3K-Akt signaling pathway
Pathways in cancer
Pathway Interaction Database LPA receptor mediated events
Reactome G alpha (q) signalling events
G alpha (i) signalling events
Lysosphingolipid and LPA receptors
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 540635(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4031).
Ref 526598Fatty alcohol phosphates are subtype-selective agonists and antagonists of lysophosphatidic acid receptors. Mol Pharmacol. 2003 May;63(5):1032-42.

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