Drug Information

Drug General Information
Drug ID
D0P4GP
Former ID
DIB020768
Drug Name
PSB1114
Synonyms
PSB-1114; PSB 1114
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541195]
Formula
C10H15F2N2O13P3S
InChI
InChI=1S/C10H15F2N2O13P3S/c11-10(12,28(18,19)20)29(21,22)27-30(23,24)25-3-4-6(15)7(16)8(26-4)14-2-1-5(31)13-9(14)17/h1-2,4,6-8,15-16H,3H2,(H,21,22)(H,23,24)(H,13,17,31)(H2,18,19,20)/t4-,6-,7-,8-/m1/s1
InChIKey
DFGBPSGNGNHNQM-XVFCMESISA-N
PubChem Compound ID
52952605
PubChem Substance ID
123104246, 131280487, 131344837, 178102525
Target and Pathway
Target(s) P2Y purinoceptor 2 Target Info Agonist [531402]
KEGG Pathway Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
NetPath Pathway IL5 Signaling Pathway
Reactome G alpha (q) signalling events
P2Y receptors
Surfactant metabolism
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 541195(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5902).
Ref 531402Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors. J Med Chem. 2011 Apr 28;54(8):2878-90.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.