Drug Information

Drug General Information
Drug ID
D0M3LU
Former ID
DNC003466
Drug Name
3,4-Dihydro-5-Methyl-Isoquinolinone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Formula
C10H11NO
Canonical SMILES
CC1=CC=CC2=C1CCNC2=O
InChI
1S/C10H11NO/c1-7-3-2-4-9-8(7)5-6-11-10(9)12/h2-4H,5-6H2,1H3,(H,11,12)
InChIKey
RLLZPXDJYADIEU-UHFFFAOYSA-N
PubChem Compound ID
148140
PubChem Substance ID
6822195, 7887029, 10249817, 14772446, 26697308, 26709828, 46225093, 46507396, 57346709, 57560196, 80171018, 87225373, 93578787, 99451373, 103354750, 103855820, 104418317, 125737608, 129146463, 134342466, 135258486, 137140272, 149742736, 160833627, 160966815, 162277392, 162784464, 163396166, 163884588, 196394206, 202819545, 204385209, 223554826, 224954210, 227105146, 242073679, 249762443, 249783963, 249800522, 249815921, 249832387, 250165778, 250207458, 251966590, 252056272, 252430822, 252489777
Target and Pathway
Target(s) Poly [ADP-ribose] polymerase-1 Target Info Inhibitor [551393]
KEGG Pathway Base excision repair
NF-kappa B signaling pathway
PANTHER Pathway FAS signaling pathway
Pathway Interaction Database Integrin-linked kinase signaling
Caspase Cascade in Apoptosis
Notch-mediated HES/HEY network
Reactome Dual Incision in GG-NER
WikiPathways FAS pathway and Stress induction of HSP regulation
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Nanoparticle triggered regulated necrosis
Corticotropin-releasing hormone
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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