Drug Information

Drug General Information
Drug ID
D06RAM
Former ID
DIB020384
Drug Name
MM 11253
Synonyms
MM-11253; MM11253
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540657]
Formula
C28H30O2S2
InChI
InChI=1S/C28H30O2S2/c1-26(2)11-12-27(3,4)24-17-22(9-10-23(24)26)28(31-13-14-32-28)21-8-7-18-15-20(25(29)30)6-5-19(18)16-21/h5-10,15-17H,11-14H2,1-4H3,(H,29,30)
InChIKey
DPVGXUNWCVEIGT-UHFFFAOYSA-N
PubChem Compound ID
10389639
PubChem Substance ID
15405236, 34109247, 74526726, 140288021, 163125606, 178100886, 204366766, 229468642, 241376650, 248879036, 249617992, 252109994, 252157558
Target and Pathway
Target(s) Retinoic acid receptor gamma Target Info Antagonist [525726]
Reactome Nuclear Receptor transcription pathway
WikiPathways Vitamin A and Carotenoid Metabolism
Nuclear Receptors in Lipid Metabolism and Toxicity
Mesodermal Commitment Pathway
Endoderm Differentiation
Nuclear Receptors
References
Ref 540657(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4062).
Ref 525726Modulation of retinoic acid receptor function alters the growth inhibitory response of oral SCC cells to retinoids. Oncogene. 2000 Mar 9;19(11):1457-65.

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