Drug Information

Drug General Information
Drug ID
D08HFG
Former ID
DIB019287
Drug Name
compound 18
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531180]
Formula
C15H13N5O
InChI
InChI=1S/C15H13N5O/c16-14(21)10-8-12(11-6-7-18-15(17)20-11)19-13(10)9-4-2-1-3-5-9/h1-8,19H,(H2,16,21)(H2,17,18,20)
InChIKey
VOQXQYXTZZHYBF-UHFFFAOYSA-N
PubChem Compound ID
24809764
PubChem Substance ID
49756559, 57124658, 85202070, 123088777, 123108542, 137516515, 138296855, 180418933, 227440917, 247532070, 249565871
Target and Pathway
Target(s) TAO kinase 1 Target Info Inhibitor [531180]
Cell division protein kinase 9 Target Info Inhibitor [531180]
CDC7 protein kinase Target Info Inhibitor [531180]
KEGG Pathway Transcriptional misregulation in cancer
NetPath Pathway EGFR1 Signaling PathwayNetPath_7:TGF_beta_Receptor Signaling Pathway
Reactome SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
WikiPathways Cardiac Hypertrophic Response
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Host Interactions of HIV factors
HIV Life Cycle
IL-9 Signaling Pathway
RNA Polymerase II Transcription
MicroRNAs in cardiomyocyte hypertrophy
References
Ref 531180Cdc7 kinase inhibitors: 5-heteroaryl-3-carboxamido-2-aryl pyrroles as potential antitumor agents. 1. Lead finding. J Med Chem. 2010 Oct 28;53(20):7296-315.
Ref 531180Cdc7 kinase inhibitors: 5-heteroaryl-3-carboxamido-2-aryl pyrroles as potential antitumor agents. 1. Lead finding. J Med Chem. 2010 Oct 28;53(20):7296-315.

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