Drug Information

Drug General Information
Drug ID
D0K8DY
Former ID
DNC010283
Drug Name
9-(N-benzylaminomethyl)-9,10-dihydroanthracene
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530613]
Formula
C22H21N
Canonical SMILES
C1C2=CC=CC=C2C(C3=CC=CC=C31)CNCC4=CC=CC=C4
InChI
1S/C22H21N/c1-2-8-17(9-3-1)15-23-16-22-20-12-6-4-10-18(20)14-19-11-5-7-13-21(19)22/h1-13,22-23H,14-16H2
InChIKey
PJLWLZAKVLPHRL-UHFFFAOYSA-N
PubChem Compound ID
44373281
Target and Pathway
Target(s) 5-hydroxytryptamine 2A receptor Target Info Inhibitor [530613]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and STAT3 Signaling
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 530613Bioorg Med Chem Lett. 2010 Feb 1;20(3):935-8. Epub 2009 Dec 23.9-Aminomethyl-9,10-dihydroanthracene (AMDA) analogs as structural probes for steric tolerance in 5-HT2A and H1 receptor binding sites.
Ref 530613Bioorg Med Chem Lett. 2010 Feb 1;20(3):935-8. Epub 2009 Dec 23.9-Aminomethyl-9,10-dihydroanthracene (AMDA) analogs as structural probes for steric tolerance in 5-HT2A and H1 receptor binding sites.

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