Drug Information

Drug General Information
Drug ID
D06QVB
Former ID
DNC004907
Drug Name
4-(Naphthalene-1-sulfonyl)-phenylamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527463]
Formula
C16H13NO2S
Canonical SMILES
C1=CC=C2C(=C1)C=CC=C2S(=O)(=O)C3=CC=C(C=C3)N
InChI
1S/C16H13NO2S/c17-13-8-10-14(11-9-13)20(18,19)16-7-3-5-12-4-1-2-6-15(12)16/h1-11H,17H2
InChIKey
WJMHQZIDRDGGIY-UHFFFAOYSA-N
PubChem Compound ID
44390054
Target and Pathway
Target(s) 5-hydroxytryptamine 6 receptor Target Info Inhibitor [527463]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 527463Bioorg Med Chem Lett. 2005 Mar 15;15(6):1707-11.1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands.
Ref 527463Bioorg Med Chem Lett. 2005 Mar 15;15(6):1707-11.1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands.

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