Drug Information

Drug General Information
Drug ID
D00VHS
Former ID
DNC013860
Drug Name
4-(5-(4-Hydroxyphenyl)isothiazol-4-yl)phenol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529881]
Formula
C15H11NO2S
Canonical SMILES
C1=CC(=O)C=CC1=C2C(=CNS2)C3=CC=C(C=C3)O
InChI
1S/C15H11NO2S/c17-12-5-1-10(2-6-12)14-9-16-19-15(14)11-3-7-13(18)8-4-11/h1-9,16-17H
InChIKey
WTBNBQYDOKCYAL-UHFFFAOYSA-N
PubChem Compound ID
44564459
Target and Pathway
Target(s) Prostaglandin G/H synthase 1 Target Info Inhibitor [529881]
BioCyc Pathway C20 prostanoid biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Platelet activation
Serotonergic synapse
NetPath Pathway TGF_beta_Receptor Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Prostaglandin Synthesis and Regulation
Arachidonic acid metabolism
Phase 1 - Functionalization of compounds
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 529881Bioorg Med Chem. 2009 Jan 15;17(2):558-68. Epub 2008 Dec 6.Diaryl-dithiolanes and -isothiazoles: COX-1/COX-2 and 5-LOX-inhibitory, *OH scavenging and anti-adhesive activities.
Ref 529881Bioorg Med Chem. 2009 Jan 15;17(2):558-68. Epub 2008 Dec 6.Diaryl-dithiolanes and -isothiazoles: COX-1/COX-2 and 5-LOX-inhibitory, *OH scavenging and anti-adhesive activities.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.