Drug Information

Drug General Information
Drug ID
D0F1VR
Former ID
DNC005189
Drug Name
3,4-Dibromo-2-(5-bromo-2-hydroxy-phenoxy)-phenol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527145]
Formula
C12H7Br3O3
Canonical SMILES
C1=CC(=C(C=C1Br)OC2=C(C=CC(=C2Br)Br)O)O
InChI
1S/C12H7Br3O3/c13-6-1-3-8(16)10(5-6)18-12-9(17)4-2-7(14)11(12)15/h1-5,16-17H
InChIKey
MQTQEJZMDKSDNZ-UHFFFAOYSA-N
PubChem Compound ID
44396194
Target and Pathway
Target(s) Arachidonate 15-lipoxygenase Target Info Inhibitor [527145]
BioCyc Pathway Resolvin D biosynthesis
Lipoxin biosynthesis
KEGG Pathway Arachidonic acid metabolism
Linoleic acid metabolism
Metabolic pathways
Serotonergic synapse
NetPath Pathway IL4 Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
Pathway Interaction Database IL4-mediated signaling events
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Arachidonic acid metabolism
Eicosanoid Synthesis
References
Ref 527145J Med Chem. 2004 Jul 29;47(16):4060-5.Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase.
Ref 527145J Med Chem. 2004 Jul 29;47(16):4060-5.Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase.

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