Drug Information

Drug General Information
Drug ID
D0WK9R
Former ID
DIB020677
Drug Name
PF-06447475
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533011]
Formula
C17H15N5O
InChI
InChI=1S/C17H15N5O/c18-9-12-2-1-3-13(8-12)14-10-19-16-15(14)17(21-11-20-16)22-4-6-23-7-5-22/h1-3,8,10-11H,4-7H2,(H,19,20,21)
InChIKey
BHTWDJBVZQBRKP-UHFFFAOYSA-N
PubChem Compound ID
72706840
PubChem Substance ID
172107970, 224723379, 240350020, 249565386, 249565734, 251910776, 252451026
Target and Pathway
Target(s) leucine-rich repeat kinase 2 Target Info Inhibitor [533011]
References
Ref 533011Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. J Med Chem. 2015 Jan 8;58(1):419-32.
Ref 533011Discovery and preclinical profiling of 3-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor. J Med Chem. 2015 Jan 8;58(1):419-32.

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