Drug Information

Drug General Information
Drug ID
D0ZP2D
Former ID
DIB020472
Drug Name
N-1-isopropyl-5-MeOT
Synonyms
N-1-isopropyl-5-methoxytryptamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538958]
Formula
C14H20N2O
InChI
InChI=1S/C14H20N2O/c1-10(2)16-9-11(6-7-15)13-8-12(17-3)4-5-14(13)16/h4-5,8-10H,6-7,15H2,1-3H3
InChIKey
WFNIDMQOBQYSBC-UHFFFAOYSA-N
PubChem Compound ID
24820144
PubChem Substance ID
49830331, 84997461, 104824605, 135650392, 136351036, 143450086
Target and Pathway
Target(s) 5-hydroxytryptamine 2A receptor Target Info Agonist [533905]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and STAT3 Signaling
Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 538958(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 158).
Ref 533905Species variations in transmembrane region V of the 5-hydroxytryptamine type 2A receptor alter the structure-activity relationship of certain ergolines and tryptamines. Mol Pharmacol. 1994 Feb;45(2):277-86.

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