Drug Information

Drug General Information
Drug ID
D0Z8CQ
Drug Name
Sarilumab
Synonyms
Kevzara
Drug Type
Monoclonal antibody
Indication Severely active rheumatoid arthritis [ICD10:M05-M06] Approved [889446]
Company
Sanofi Synthelabo
Target and Pathway
Target(s) Interleukin-6 receptor Target Info Modulator [556264]
KEGG Pathway Cytokine-cytokine receptor interaction
HIF-1 signaling pathway
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
Non-alcoholic fatty liver disease (NAFLD)
Reactome MAPK3 (ERK1) activation
MAPK1 (ERK2) activation
WikiPathways SIDS Susceptibility Pathways
Senescence and Autophagy in Cancer
IL-6 signaling pathway
Differentiation Pathway
Interleukin-6 signaling
References
Ref 889446Drugs@FDA (Edaravone)
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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