Drug Information

Drug General Information
Drug ID
D0Z6GG
Former ID
DNC014361
Drug Name
N-benzyl-2-(pyrrolidin-1-yl)pyrimidin-4-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530923]
Formula
C15H18N4
Canonical SMILES
C1CCN(C1)C2=NC=CC(=N2)NCC3=CC=CC=C3
InChI
1S/C15H18N4/c1-2-6-13(7-3-1)12-17-14-8-9-16-15(18-14)19-10-4-5-11-19/h1-3,6-9H,4-5,10-12H2,(H,16,17,18)
InChIKey
PGBNXXDXGXQQRQ-UHFFFAOYSA-N
PubChem Compound ID
46891014
Target and Pathway
Target(s) Acetylcholinesterase Target Info Inhibitor [530923]
KEGG Pathway Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
WikiPathways Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 530923Bioorg Med Chem Lett. 2010 Jun 15;20(12):3606-9. Epub 2010 Apr 28.Design, synthesis and evaluation of 2,4-disubstituted pyrimidines as cholinesterase inhibitors.
Ref 530923Bioorg Med Chem Lett. 2010 Jun 15;20(12):3606-9. Epub 2010 Apr 28.Design, synthesis and evaluation of 2,4-disubstituted pyrimidines as cholinesterase inhibitors.

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