Drug Information

Drug General Information
Drug ID
D0YW6P
Former ID
DIB014762
Drug Name
RU-101
Synonyms
RU-10; Recombinant human serum albumin (ocular, dry eye), R-Tech Ueno
Indication Xerophthalmia [ICD10:E50.6-E50.7] Phase 1/2 [524273]
Company
R-tech ueno
Target and Pathway
Target(s) Serum albumin Target Info Modulator [544031]
Pathway Interaction Database FOXA2 and FOXA3 transcription factor networks
Reactome Platelet degranulation
Recycling of bile acids and salts
HDL-mediated lipid transport
Scavenging of heme from plasma
WikiPathways Human Complement System
Binding and Uptake of Ligands by Scavenger Receptors
Lipid digestion, mobilization, and transport
Transport of vitamins, nucleosides, and related molecules
Bile acid and bile salt metabolism
Folate Metabolism
Vitamin B12 Metabolism
Selenium Micronutrient Network
References
Ref 524273ClinicalTrials.gov (NCT01843894) A Phase 1/2, RU-101 Ophthalmic Solution in Patients With Severe Dry Eye. U.S. National Institutes of Health.
Ref 544031Albumin as a tear supplement in the treatment of severe dry eye. Br J Ophthalmol. 2003 October; 87(10): 1279-1283.

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