Drug Information

Drug General Information
Drug ID
D0Y9XK
Former ID
DNC010910
Drug Name
1-phenyl-2-(1-phenyl-1H-tetrazol-5-yloxy)ethanone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530901]
Formula
C16H13N3O2
Canonical SMILES
C1=CC=C(C=C1)C(=O)COC2=CN=NN2C3=CC=CC=C3
InChI
1S/C16H13N3O2/c20-15(13-7-3-1-4-8-13)12-21-16-11-17-18-19(16)14-9-5-2-6-10-14/h1-11H,12H2
InChIKey
NFBZAZXCZDAVSL-UHFFFAOYSA-N
PubChem Compound ID
46890243
Target and Pathway
Target(s) Corticosteroid 11-beta-dehydrogenase, isozyme 1 Target Info Inhibitor [530901]
KEGG Pathway Steroid hormone biosynthesis
Metabolism of xenobiotics by cytochrome P450
Metabolic pathways
Chemical carcinogenesis
NetPath Pathway IL1 Signaling Pathway
FSH Signaling Pathway
PathWhiz Pathway Steroidogenesis
Reactome Glucocorticoid biosynthesis
WikiPathways Prostaglandin Synthesis and Regulation
Metabolism of steroid hormones and vitamin D
Glucocorticoid & Mineralcorticoid Metabolism
References
Ref 530901Bioorg Med Chem Lett. 2010 Jun 1;20(11):3265-71. Epub 2010 Apr 18.Modulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by 1,5-substituted 1H-tetrazoles.
Ref 530901Bioorg Med Chem Lett. 2010 Jun 1;20(11):3265-71. Epub 2010 Apr 18.Modulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by 1,5-substituted 1H-tetrazoles.

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