Drug Information

Drug General Information
Drug ID
D0Y7ND
Former ID
DNC013252
Drug Name
4-amino-N-(2-chlorophenyl)benzenesulfonamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528508]
Formula
C12H11ClN2O2S
Canonical SMILES
C1=CC=C(C(=C1)NS(=O)(=O)C2=CC=C(C=C2)N)Cl
InChI
1S/C12H11ClN2O2S/c13-11-3-1-2-4-12(11)15-18(16,17)10-7-5-9(14)6-8-10/h1-8,15H,14H2
InChIKey
XZQHDUUDKCHQIL-UHFFFAOYSA-N
PubChem Compound ID
3405810
Target and Pathway
Target(s) Prostaglandin G/H synthase 1 Target Info Inhibitor [528508]
BioCyc Pathway C20 prostanoid biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Platelet activation
Serotonergic synapse
NetPath Pathway TGF_beta_Receptor Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Prostaglandin Synthesis and Regulation
Arachidonic acid metabolism
Phase 1 - Functionalization of compounds
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 528508Bioorg Med Chem. 2007 Jan 15;15(2):1014-21. Epub 2006 Oct 18.Analgesic agents without gastric damage: design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1-selectiveinhibitors.
Ref 528508Bioorg Med Chem. 2007 Jan 15;15(2):1014-21. Epub 2006 Oct 18.Analgesic agents without gastric damage: design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1-selectiveinhibitors.

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