Drug Information

Drug General Information
Drug ID
D0Y2SE
Former ID
DIB001962
Drug Name
Alpha-glucosidase
Synonyms
Pompes disease therapy, Pharming; Alpha-glucosidase (transgenic); Alpha-glucosidase, Pharming; GD-halpha-GLU; Alpha-glucosidase (transgenic), Pharming/Genzyme
Indication Muscle disease [ICD10:M60-M63] Phase 3 [523686]
Company
Pharming Group NV
CAS Number
CAS 9001-42-7
Target and Pathway
Target(s) Maltase-glucoamylase, intestinal Target Info Modulator [543667]
KEGG Pathway Galactose metabolism
Starch and sucrose metabolism
Metabolic pathways
Carbohydrate digestion and absorption
PathWhiz Pathway Starch and Sucrose Metabolism
WikiPathways Metabolism of carbohydrates
References
Ref 523686ClinicalTrials.gov (NCT01468181) A Study of LY2189265 in Japanese Participants With Type 2 Diabetes Mellitus. U.S. National Institutes of Health.
Ref 543667(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2627).

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