Drug Information

Drug General Information
Drug ID
D0XL4I
Former ID
DPR000135
Drug Name
ER-319711-15
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Preclinical [528437]
Company
Eisai Co Ltd
Target and Pathway
Target(s) Dipeptidyl peptidase IV Target Info Inhibitor [537022]
KEGG Pathway Protein digestion and absorption
NetPath Pathway IL2 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
References
Ref 5284377-But-2-ynyl-9-(6-methoxy-pyridin-3-yl)-6-piperazin-1-yl-7,9-dihydro-purin-8-one is a novel competitive and selective inhibitor of dipeptidyl peptidase IV with an antihyperglycemic activity. J Pharmacol Exp Ther. 2006 Dec;319(3):1253-7. Epub 2006 Sep 15.
Ref 537022Emerging drug candidates of dipeptidyl peptidase IV (DPP IV) inhibitor class for the treatment of Type 2 Diabetes. Curr Drug Targets. 2009 Jan;10(1):71-87.

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