Drug Information

Drug General Information
Drug ID
D0X3TF
Former ID
DIB019649
Drug Name
CP55,667
Synonyms
CP 55,667; CP-55,667
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540947]
Formula
C24H40O3
InChI
InChI=1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3
InChIKey
YNZFFALZMRAPHQ-UHFFFAOYSA-N
PubChem Compound ID
4412255
PubChem Substance ID
6503055, 10170157, 15498335, 35760042, 50628870, 85208875, 103856321, 112928023, 125093030, 125334030, 125334235, 125569692, 129823212, 131327402, 137226643, 137746908, 162022881, 162918582, 172846812, 177748589, 178102206, 178126825, 201505317, 226870916, 241164086, 250027746, 252367050
Target and Pathway
Target(s) G-protein coupled receptor 55 Target Info Antagonist [531335]
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 540947(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5570).
Ref 531335Pharmacology of GPR55 in yeast and identification of GSK494581A as a mixed-activity glycine transporter subtype 1 inhibitor and GPR55 agonist. J Pharmacol Exp Ther. 2011 Apr;337(1):236-46.

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