Drug Information

Drug General Information
Drug ID
D0W9ZV
Former ID
DNC014895
Drug Name
AW-00430
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531262]
Formula
C14H10BrClN2O2S3
Canonical SMILES
CC1=NC(=CS1)C2=CC=C(S2)S(=O)(=O)NC3=C(C=C(C=C3)Br)Cl
InChI
1S/C14H10BrClN2O2S3/c1-8-17-12(7-21-8)13-4-5-14(22-13)23(19,20)18-11-3-2-9(15)6-10(11)16/h2-7,18H,1H3
InChIKey
AMNKYHFERGWVCB-UHFFFAOYSA-N
PubChem Compound ID
2795741
Target and Pathway
Target(s) Calpain Target Info Inhibitor [531262]
KEGG Pathway Protein processing in endoplasmic reticulum
Apoptosis
Alzheimer's disease
Reactome Degradation of the extracellular matrix
WikiPathways Focal Adhesion
Integrated Pancreatic Cancer Pathway
Alzheimers Disease
Integrin-mediated Cell Adhesion
References
Ref 531262Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2).
Ref 531262Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. Epub 2010 Oct 21.In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2).

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