Drug Information

Drug General Information
Drug ID
D0W3XP
Former ID
DNC009464
Drug Name
Garveatin C
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528499]
Formula
C22H24O5
Canonical SMILES
CC1=CC2=CC3=C(C(=C2C(=C1C(=O)C)OC)O)C(=O)C(C(=O)C3(C)C)<br />(C)C
InChI
1S/C22H24O5/c1-10-8-12-9-13-16(19(25)22(5,6)20(26)21(13,3)4)17(24)15(12)18(27-7)14(10)11(2)23/h8-9,24H,1-7H3
InChIKey
BRECKZGJFRHNPM-UHFFFAOYSA-N
PubChem Compound ID
356405
Target and Pathway
Target(s) Indoleamine 2,3-dioxygenase Target Info Inhibitor [528499]
BioCyc Pathway Superpathway of tryptophan utilization
Tryptophan degradation
L-kynurenine degradation
Tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
NAD de novo biosynthesis
KEGG Pathway Tryptophan metabolism
Metabolic pathways
African trypanosomiasis
NetPath Pathway TSLP Signaling Pathway
IL5 Signaling Pathway
TGF_beta_Receptor Signaling Pathway
PathWhiz Pathway Tryptophan Metabolism
Reactome Tryptophan catabolism
WikiPathways Tryptophan metabolism
Metabolism of amino acids and derivatives
References
Ref 528499J Nat Prod. 2006 Oct;69(10):1496-9.Indoleamine 2,3-dioxygenase inhibitors from the Northeastern Pacific Marine Hydroid Garveia annulata.
Ref 528499J Nat Prod. 2006 Oct;69(10):1496-9.Indoleamine 2,3-dioxygenase inhibitors from the Northeastern Pacific Marine Hydroid Garveia annulata.

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