Drug Information

Drug General Information
Drug ID
D0W3VM
Former ID
DNC006879
Drug Name
N-(4-tert-butylphenyl)-4-(pyridin-2-yl)benzamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528334]
Formula
C22H22N2O
Canonical SMILES
CC(C)(C)C1=CC=C(C=C1)NC(=O)C2=CC=C(C=C2)C3=CC=CC=N3
InChI
1S/C22H22N2O/c1-22(2,3)18-11-13-19(14-12-18)24-21(25)17-9-7-16(8-10-17)20-6-4-5-15-23-20/h4-15H,1-3H3,(H,24,25)
InChIKey
JWPYMHAYISNKIC-UHFFFAOYSA-N
PubChem Compound ID
11472986
Target and Pathway
Target(s) Vanilloid receptor Target Info Inhibitor [528334]
Vanilloid receptor 1 Target Info Inhibitor [528334]
KEGG Pathway Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database Trk receptor signaling mediated by the MAPK pathway
Trk receptor signaling mediated by PI3K and PLC-gamma
Reactome TRP channels
References
Ref 528334Bioorg Med Chem Lett. 2006 Oct 1;16(19):5217-21. Epub 2006 Jul 25.From arylureas to biarylamides to aminoquinazolines: discovery of a novel, potent TRPV1 antagonist.
Ref 528334Bioorg Med Chem Lett. 2006 Oct 1;16(19):5217-21. Epub 2006 Jul 25.From arylureas to biarylamides to aminoquinazolines: discovery of a novel, potent TRPV1 antagonist.

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