Drug Information

Drug General Information
Drug ID
D0W2QN
Former ID
DNC005763
Drug Name
2-Ethyl-5-methoxy-3-piperidin-4-yl-1H-indole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527665]
Formula
C16H22N2O
Canonical SMILES
CCC1=C(C2=C(N1)C=CC(=C2)OC)C3CCNCC3
InChI
1S/C16H22N2O/c1-3-14-16(11-6-8-17-9-7-11)13-10-12(19-2)4-5-15(13)18-14/h4-5,10-11,17-18H,3,6-9H2,1-2H3
InChIKey
UMTBQNCFQQORNJ-UHFFFAOYSA-N
PubChem Compound ID
44403334
Target and Pathway
Target(s) 5-hydroxytryptamine 6 receptor Target Info Inhibitor [527665]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 527665Bioorg Med Chem Lett. 2005 Oct 1;15(19):4230-4.2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists.
Ref 527665Bioorg Med Chem Lett. 2005 Oct 1;15(19):4230-4.2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Tang and Dr. Zhang.