Drug Information

Drug General Information
Drug ID
D0W2HW
Former ID
DNC007095
Drug Name
N,N-diethyl-2-(1H-indol-3-yl)ethanamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528416]
Formula
C14H20N2
Canonical SMILES
CCN(CC)CCC1=CNC2=CC=CC=C21
InChI
1S/C14H20N2/c1-3-16(4-2)10-9-12-11-15-14-8-6-5-7-13(12)14/h5-8,11,15H,3-4,9-10H2,1-2H3
InChIKey
LSSUMOWDTKZHHT-UHFFFAOYSA-N
CAS Number
CAS 61-51-8
PubChem Compound ID
6090
Target and Pathway
Target(s) 5-hydroxytryptamine 6 receptor Target Info Inhibitor [528416]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 528416Bioorg Med Chem Lett. 2006 Nov 15;16(22):5832-5. Epub 2006 Aug 30.Interaction of N1-unsubstituted and N1-benzenesulfonyltryptamines at h5-HT6 receptors.
Ref 528416Bioorg Med Chem Lett. 2006 Nov 15;16(22):5832-5. Epub 2006 Aug 30.Interaction of N1-unsubstituted and N1-benzenesulfonyltryptamines at h5-HT6 receptors.

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