Drug Information

Drug General Information
Drug ID
D0W0SE
Former ID
DIB020685
Drug Name
PF750
Synonyms
PF-750; PF 750
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540712]
Formula
C22H23N3O
InChI
InChI=1S/C22H23N3O/c26-22(24-20-7-2-1-3-8-20)25-12-10-17(11-13-25)14-18-15-19-6-4-5-9-21(19)23-16-18/h1-9,15-17H,10-14H2,(H,24,26)
InChIKey
BIODYGOZWZNCAG-UHFFFAOYSA-N
PubChem Compound ID
25154868
PubChem Substance ID
57248832, 57298452, 67094290, 81025687, 103684898, 123220354, 125335680, 135698845, 162248588, 163124909, 164764181, 177748614, 178101928, 196409632, 198985705, 204362032, 223370243, 241376374, 245337266, 252157180, 252216032
Target and Pathway
Target(s) Fatty-acid amide hydrolase Target Info Inhibitor [529113]
BioCyc Pathway Anandamide degradation
KEGG Pathway Retrograde endocannabinoid signaling
PANTHER Pathway Anandamide degradation
References
Ref 540712(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5244).
Ref 529113Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry. 2007 Nov 13;46(45):13019-30. Epub 2007 Oct 19.

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