Drug Information

Drug General Information
Drug ID
D0VA4Y
Former ID
DCL000928
Drug Name
Phentermine+topiramate
Synonyms
Qnexa (TN)
Drug Type
Small molecular drug
Indication Obesity [ICD9: 278; ICD10:E66] Phase 3 [536869]
Company
Vivus
Formula
C22H36N2O8S
Canonical SMILES
CC1(OC2COC3(C(C2O1)OC(O3)(C)C)COS(=O)(=O)N)C.CC(C)(CC1=<br />CC=CC=C1)N
InChI
1S/C12H21NO8S.C10H15N/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12;1-10(2,11)8-9-6-4-3-5-7-9/h7-9H,5-6H2,1-4H3,(H2,13,14,15);3-7H,8,11H2,1-2H3/t7-,8-,9?,12+;/m1./s1
InChIKey
PWDLDBWXTVILPC-QGGVPXFVSA-N
CAS Number
CAS 122-09-8
PubChem Compound ID
56842108
PubChem Substance ID
135264386
ChEBI ID
ChEBI:8080
SuperDrug ATC ID
C01CA11
SuperDrug CAS ID
cas=000100925
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor Target Info Modulator [536710]
Carbonic anhydrase Target Info Inhibitor [536710]
References
Ref 536869Adjunctive topiramate enhances the risk of hypothermia associated with valproic acid therapy. J Clin Pharm Ther. 2008 Oct;33(5):513-9.
Ref 536710Anti-obesity drugs. Expert Opin Pharmacother. 2008 Jun;9(8):1339-50.

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