Drug Information

Drug General Information
Drug ID
D0V6OH
Former ID
DIB020459
Drug Name
MTSEA
Synonyms
methanethiosulfonate ethylammonium
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541425]
Formula
C3H9NO2S2
InChI
InChI=1S/C3H9NO2S2/c1-8(5,7)6-3-2-4/h2-4H2,1H3
InChIKey
HKERMLQDWIEJQS-UHFFFAOYSA-N
PubChem Compound ID
53443082
PubChem Substance ID
128072726, 137275620, 178102892, 226759966
Target and Pathway
Target(s) Transient receptor potential cation channel subfamily A member 1 Target Info Activator [528629]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 541425(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6272).
Ref 528629Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature. 2007 Feb 1;445(7127):541-5. Epub 2007 Jan 21.

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