Drug Information

Drug General Information
Drug ID
D0V5XL
Former ID
DIB005608
Drug Name
KRI-1314
Drug Type
Small molecular drug
Indication Hypertension [ICD9: 401; ICD10:I10-I16] Terminated [545182]
Company
Kissei Pharmaceutical Co Ltd
Formula
C38H51N5O7
Canonical SMILES
C(=O)([C@@H]([C@@H](NC(=O)[C@@H](NC(=O)[C@@H](CC(=O)N1C<br />COCC1)Cc1c2c(ccc1)cccc2)Cc1nc[nH]c1)CC1CCCCC1)O)OC(C)C
CAS Number
CAS 128053-53-2
PubChem Compound ID
6918046
Target and Pathway
Target(s) Renin, renal Target Info Inhibitor [533964]
KEGG Pathway Renin-angiotensin system
PathWhiz Pathway Angiotensin Metabolism
Reactome Metabolism of Angiotensinogen to Angiotensins
WikiPathways ACE Inhibitor Pathway
Metabolism of Angiotensinogen to Angiotensins
References
Ref 545182Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002396)
Ref 533964KRI-1314: an orally effective inhibitor of human renin. Jpn J Pharmacol. 1993 Sep;63(1):109-19.

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