Drug Information

Drug General Information
Drug ID
D0V4FT
Former ID
DIB020432
Drug Name
MRS2567
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539104]
Formula
C16H12N2S2
InChI
InChI=1S/C16H12N2S2/c19-11-17-15-7-3-13(4-8-15)1-2-14-5-9-16(10-6-14)18-12-20/h3-10H,1-2H2
InChIKey
KGPFLJVFCCOOEO-UHFFFAOYSA-N
PubChem Compound ID
11266452
PubChem Substance ID
16352481, 23440823, 42345946, 78777168, 128379434, 135650660, 228024373
Target and Pathway
Target(s) P2Y purinoceptor 6 Target Info Antagonist [527038]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome G alpha (q) signalling events
P2Y receptors
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 539104(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1752).
Ref 527038Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y6 nucleotide receptors. Biochem Pharmacol. 2004 May 1;67(9):1763-70.

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